This handbook aims to provide practical guidelines to help managers and relevant parties achieve sustainable tourism in protected and fragile areas. Drawing from the 2024 APEC workshop discussion in Bangkok, it focuses on four key areas including policy and plan development, visitor management, stakeholder participation, and tourism product development. Eleven best practices from seven APEC economies including Australia; China; Indonesia; Mexico; New Zealand; Thailand; and United States, are included. Putting these management guidelines into practice, we can protect the invaluable natural and cultural heritage of these areas for future generations while providing meaningful and enriching experiences for tourists. It is our collective responsibility to maintain a balance between tourism development and conservation, ensuring that protected and fragile areas continue to thrive and inspire for years to come.